According to the medical dictionary, VWD is an inherited autosomal recessive disease in which abnormally slow coagulation of blood may lead to spontaneous and excessive bleeding following an injury. Huh! In simpler terms von Willebrand disease is the most common inherited bleeding disorder, in which a clotting protein called von Willebrand factor is deficient or defective.
There are three different types of VWD and they are as followed:
Type 1 VWD is the most common form. People with Type 1 VWD have lower than normal levels of VWF. Symptoms are usually very mild. Still, it is possible for someone with Type 1 VWD to have serious bleeding.
Type 2 VWD involves a defect in the VWF structure. The VWF protein does not work properly, causing lower than normal VWF activity. There are different Type 2 VWD defects. Symptoms are usually moderate.
Type 3 VWD is usually the most serious form. People with Type 3 VWD have very little or no VWF. Symptoms are more severe. People with Type 3 VWD can have bleeding into muscles and joints, sometimes without injury. According to kidshealth.org here are some signs and symptoms. The symptoms of von Willebrand disease can include:
- bruising that’s unusual in location or frequency
- bleeding in the mucous membranes, such as the gums, nose, and lining of the gastrointestinal system
- excessive or prolonged bleeding after a tooth is pulled or tonsils are removed or prolonged oozing from cuts
- excessive or prolonged bleeding after circumcision